Curriculum Vitae

Full name: Malgorzata Maria Duszczyk
Born: 26.05.1978 in Warsaw, Poland
Citizen of: Poland & The Netherlands

Positions held

03.2010 – present: Postdoctoral Fellow, Institute of Molecular Biology & Biophysics, ETHZ
Research advisor: Frederic Allain

01.2009 – 02.2010: Postdoctoral Fellow, Institute of Structural Biology, Helmholtz Zentrum Muenchen & Department Chemie, Technische Universitaet Muenchen
Research advisor: Michael Sattler

Education & Scientific Training

10.2003 – 12.2008: EMBL International PhD Programme, European Molecular Biology Laboratory, Heidelberg, Germany
Ph.D degree in Natural Sciences & mathematics received on 06.05.2009 from the Radboud University, Nijmegen, The Netherlands
PhD thesis 'Structural Studies on Xist RNA in X-inactivation'
Thesis advisors: Sybren Wijmenga (Biophysical Chemistry, Nijmegen) & Michael Sattler (Structural & Computational Biology Unit, EMBL )

1996 – 2002: BSc & MSc degree in Chemistry, University of Leiden, The Netherlands
Emphasis on Biochemistry and Structural Biology
Research advisors: Gregg Siegal, Protein Chemistry Group, University of Leiden & Joern Werner, Campbell Group, Department of Biochemistry, University of Oxford

1996 – 2003: MA in Philosophy, University of Leiden, The Netherlands
Emphasis on Philosophy of Science – requirements to obtain MA degree met only short of the Master’s thesis

1997 – 1998: Maastricht Theatre Academy

Research Interests

· RNA architecture, folding and dynamics

· Structure, recognition & dynamics of protein-RNA complexes using biophysical and biochemical methods

Research Skills

· Extensive experience with nucleic acid structure determination by NMR

· NMR spectroscopy: data collection (hardware: Bruker; software: XwinNMR/TopSpin), data processing & analysis (software: NMRPipe, NMRView), RNA assignment, RNA structure calculation & refinement (software: Aria/CNS, AMBER)

· Sample preparation for structural biology: extensive experience with in vitro transcription & purification of RNA, protein expression & purification

· Basic molecular biology techniques: cloning, PCR, gel electrophoresis & band shift assays

Awards & Fellowships

03.2010 - 02.2011 UBS fellowship for postdoctoral work in Allain laboratory

2004 – 2007: ‘E-STAR’ Marie Curie predoctoral fellowship for Early Stage Research Training funded by the EC's FP6

2003 – 2004: EMBL predoctoral fellowship

10.2001 – 03.2002: MSc Thesis research in Oxford funded from various competitive funding sources including The Leiden University International Study Fund and The British Council

Oral presentations at international meetings

‘Structural and functional analysis of a novel tetraloop in Xist RNA A-repeats’ Duszczyk MM, Wutz A. & Sattler M – presented at:

2008 Viral and Regulatory RNAs – final meeting of the FP6 EU project ‘Functional and Structural Genomics of Viral RNAs’, Kerkrade, The Netherlands

2008 RNA 2008 yearly meeting of the RNA Society, Berlin

Attended courses & conferences, poster presentations

2009 ‘The EMBO Meeting’, Amsterdam, the Netherlands
Poster presentation: ‘The Xist RNA A-repeat comprises a novel AUCG tetraloop fold and a platform for multimerization’ Duszczyk M, Wutz A. & Sattler M

2009 ‘EMBO Conference on Chromatin and Epigenetics’, EMBL Heidelberg
Poster presentation: ‘The Xist RNA A-repeat comprises a novel AUCG tetraloop fold and a platform for multimerization’ Duszczyk M, Wutz A. & Sattler M

2007 ‘Scientific Writing’ EMBL international centre for advanced training, EMBL Heidelberg

2007 EMBO workshop ‘Viral RNA: Structure, Function and Targeting’,
EMBL Heidelberg
Poster presentation: ‘Recognition of viral RNA by the nuclear export factor TAP’ Anosova I, Duszczyk M, Gabel F, Gasch A, Pimienta G, Simon B, Conti E & Sattler M

2006 ‘XXIInd International Conference on Magnetic Resonance in Biological Systems’, Göttingen, Germany
Poster presentation: ‘Structural Characterization of a Xist RNA A-repeat by NMR’ Duszczyk M, Wutz A. & Sattler M

2006 EMBO NMR Course ‘Multidimensional NMR in Structural Biology’, Il Ciocco, Lucca, Italy
Poster presentation: ‘Structural Characterization of a Xist RNA A-repeat by NMR’ Duszczyk M, Wutz A. & Sattler M

2004 ‘Structures in Biology’, EMBL Heidelberg

2004 ‘EMBL Basic PhD course in Bioinformatics’, EMBL-EBI, Hinxton, UK

2003 ‘EMBL Basic PhD course in Molecular Biology’, EMBL Heidelberg

2003 EMBO practical course 2003: ‘Structure determination of biological macromolecules by solution NMR’

2003 BNRA course ‘Advanced NMR Spectroscopy’, Nijmegen & Utrecht, The Netherlands

2002 ‘XXth International Conference on Magnetic Resonance in Biological Systems’, Toronto, Canada

Teaching experience

2009, 2010 Teacher in practical course Organic Chemistry for 2nd year BSc students of Biochemistry and Molecular Biotechnology, TU München

2009 Teacher Biomolecular NMR practical, TU München

2006 Instructor RNA in vitro transcription practical at EMBO workshop ‘Protein expression, RNA transcription and isotope labeling for NMR’, EMBL Heidelberg

2003 – 2007 Practical instructor for high school science teachers & students at the European Learning Lab for the Life Sciences, EMBL Heidelberg

Other professional experience

10.2010 - present Postdoctoral Fellow - and staff representative in the Institutskollegium of the Institute of Molecular Biology and Biophysics

2003 – 2005 Elected student representative in the EMBL Graduate Committee – the GC is responsible for the daily management of the EMBL International PhD programme

2003 – 2008 Member of the Science & Society Committee at EMBL Heidelberg

2005 Organizer of the first EMBL PhD student retreat

2000 Conference Organization: secretary for ‘PAC Symposium – Element 2000’ (yearly symposium for all chemistry students in the Netherlands)