Group Ban

Research Interests

The main goal of the research in our laboratory is the elucidation of structure and function of large cellular assemblies involved in protein and fatty acid synthesis using a combination of crystallographic, electron microscopic and biochemical experiments.

We are studying protein synthesis with a particular emphasis on understanding various ribosomal complexes involved in co-translational protein processing, folding and targeting.

Our work on giant multifunctional enzymes involved in fatty acid synthesis offers first mechanistic insights into substrate shuttling and delivery in such megasynthases, with direct implications on our understanding of polyketide synthases and non-ribosomal peptide synthases.

Ultimately we intend to obtain a “molecular movie” of these processes at high resolution so that they can be understood at a detailed mechanistic level.

Links:

PROTEIN SYNTHESIS  - FATTY ACID SYNTHESIS - LARGE ASSEMBLIES

Open positions

If you are interested in joining the lab please click here. Highly motivated people with strong background in X-ray crystallography, molecular biology, biochemistry, chemistry or biophysics are welcome.

Contact

ETH Zurich
Prof. Dr. Nenad Ban
Institute of Molecular Biology and Biophysics
HPK H 3
Schafmattstrasse 20
8093 Zurich
SWITZERLAND

Phone: +41 (0)44 633 27 85
Fax office: +41 (0)44 633 12 46
Fax instititute: +41 (0)44 633 10 73