Publications

The following is a selection of publications:
A complete list of publications is available here.

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• Lizak C, Gerber S, Numao S, Aebi M, Locher KP.
X-ray structure of a bacterial oligosaccharyltransferase.
Nature 474: 350-355 (2011). Pubmed Abstract

• Locher KP.
Structure and mechanism of ATP-binding cassette transporters.
Philos. Trans. R. Soc. Lond. Biol. Sci. 364: 239-245 (2009). Pubmed Abstract

• Gerber S, Comellas-Bigler M, Goetz BA, Locher KP.
Structural Basis of Trans-Inhibition in a Molybdate/tungstate ABC Transporter.
Science 321: 246-250 (2008). Pubmed Abstract

• Hollenstein K, Dawson RJP, Locher KP.
Structure and mechanism of ABC transporter proteins.
Curr. Opin. Struct. Biol. 17: 412-418 (2007). Pubmed Abstract

• Hvorup RN, Goetz BA, Niederer M, Hollenstein K, Perozo E, Locher KP.
Asymmetry in the Structure of the ABC Transporter Binding Protein Complex BtuCD-BtuF.
Science 317: 1387-1390 (2007). Pubmed Abstract

• Dawson RJP, Hollenstein K, Locher KP.
Uptake or extrusion: crystal structures of full ABC transporters suggest a common mechanism. (Review)
Mol. Microbiol. 65: 250-257 (2007). Pubmed Abstract

• Hollenstein K, Frei DC, Locher KP.
Structure of an ABC transporter in complex with its binding protein.
Nature 446: 213-216 (2007). Pubmed Abstract

• Dawson RJP, Locher KP.
Structure of the multidrug ABC transporter Sav1866 from Staphylococcus aureus in complex with AMP-PNP.
FEBS Lett. 581:935-938 (2007). Pubmed Abstract

• Pinkett HW, Lee AT, Lum P, Locher KP, Rees DC.
An inward-facing conformation of a putative metal-chelate-type ABC transporter.
Science 315: 373-377 (2007). Pubmed Abstract

• Dawson RJP, Locher KP.
Structure of a bacterial multidrug ABC transporter.
Nature 443:180-185 (2006). Pubmed Abstract

• Borths EL, Poolman B, Hvorup RN, Locher KP, Rees DC.
In vitro functional characterization of BtuCD-F, the Escherichia coli ABC transporter for vitamin B₁₂ uptake.
Biochemistry 44: 16301-16309 (2005). Pubmed Abstract

• Borths EL, Locher KP, Lee AT, Rees DC.
The structure of Escherichia coli BtuF and binding to its cognate ATP binding cassette transporter.
Proc. Natl. Acad. Sci. U. S. A. 99: 16642-16647 (2002). Pubmed Abstract

• Locher KP, Lee AT, Rees DC.
The E. coli BtuCD structure: A framework for ABC transporter architecture and mechanism.
Science 296: 1091-1098 (2002). Pubmed Abstract

• Locher KP, Rees B, Koebnik R, Mitschler A, Moulinier L, Rosenbusch JP, Moras D.
Transmembrane signaling across the ligand-gated FhuA receptor: Crystal structures of free and ferrichrome-bound states reveal allosteric changes.
Cell 95: 771-778 (1998). Pubmed Abstract